HORDB

ID: hor002013
Uniprot ID: Q2AC14
Protein name: Ci-GnRH-X
Gene name: LOC664635
Organism: Ciona intestinalis (Transparent sea squirt) (Ascidia intestinalis)
Family: GnRH family
Source: Animal
Expression: NA
Disease: NA
Comments: NA
Taxonomy: Ciona (genus), Cionidae (family), Phlebobranchia (order), Ascidiacea (class), Tunicata (subphylum), Chordata (phylum), Deuterostomia, Bilateria, Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
GO MF: GO:0005179 hormone activity
GO BP: GO:0007165 signal transduction
GO CC: GO:0005576 extracellular region

Sequence: QHWSNWWIPGAPGYNG
Length: 16(22-37)
Propeptide: MHKISVCVLLVVLASIQSIEAQHWSNWWIPGAPGYNGGKRPLWKGKMEIRQNYRTTPRDHDVAEDSADEAFEHGDNSRDETAITMDDLLKKLAMIRQHEKDEQLLQRILEY
Signal peptide: MHKISVCVLLVVLASIQSIEA
Modification: NA
Glycosylation: NA
Mutagenesis: NA

Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)

hor002013_AF2.pdb

hor002013_ESM.pdb

Mass:	213775	Formula:	C89H112N24O22
Absent amino acids:	CDEFKLMRTV	Common amino acids:	GW
pI:	7.54	Basic residues:	1
Polar residues:	7	Hydrophobic residues:	5
Hydrophobicity:	-103.75	Boman Index:	-1048
Half-Life / Aliphatic Index:	0.8 hour	Aliphatic Index:	30.63
Instability Index:	-867.5	Extinction Coefficient cystines:	17990
Absorbance 280nm:	1199.33

PubMed ID: 21467196
Title: Peptidomic Analysis of the Central Nervous System of the Protochordate, Ciona Intestinalis: Homologs and Prototypes of Vertebrate Peptides and Novel Peptides